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Results for "

Antispasmodic Agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) AMPK (1) Calcium Channel (5) COMT (1) Drug Metabolite (1) Histamine Receptor (1) Keap1-Nrf2 (1) mAChR (10) NF-κB (1) Phosphodiesterase (PDE) (2) Potassium Channel (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (3) Metabolic Disease (2) Neurological Disease (15)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116755

Tiropramide

CR 605
Others Others

Tiropramide is an antispasmodic agent that plays important roles in spasmodic pain of the hepatobiliary and urinary tract .

Tiropramide CR 605	Others	Others
Tiropramide is an antispasmodic agent that plays important roles in spasmodic pain of the hepatobiliary and urinary tract .

HY-118524A

Dipiproverine hydrochloride LD-935	Others	Neurological Disease
Dipiproverine (hydrochloride) is the hydrochloride form of Dipiproverine (HY-118524). Dipiproverine (hydrochloride) is an alpha-amino acid ester, an antispasmodic compound, which is used as an anticholinergic agent .

HY-W201842

Octamylamine

mAChR Neurological Disease

Octamylamine is an anticholinergic and antispasmodic agent .
HY-122086

Prifinium bromide

mAChR Neurological Disease

Prifinium bromide is antimuscarinic agent with antispasmodic, antiemetic effect .
HY-105652

Ambucetamide

Others Neurological Disease

Ambucetamide is an antispasmodic agent. Ambucetamide alleviates menstrual pain .

Octamylamine	mAChR	Neurological Disease
Octamylamine is an anticholinergic and antispasmodic agent .

Prifinium bromide	mAChR	Neurological Disease
Prifinium bromide is antimuscarinic agent with antispasmodic, antiemetic effect .

Ambucetamide	Others	Neurological Disease
Ambucetamide is an antispasmodic agent. Ambucetamide alleviates menstrual pain .

HY-N4113

Glycycoumarin	Keap1-Nrf2 AMPK	Cancer
Glycycoumarin is a potent *antispasmodic* agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-107349

Fenoverine Spasmopriv	Calcium Channel	Neurological Disease
Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents . Fenoverine induces rhabdomyolysis .

HY-105771

Parapenzolate bromide

mAChR Neurological Disease

Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent .

Parapenzolate bromide	mAChR	Neurological Disease
Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent .

HY-12769

Mebeverine acid Mebeverine metabolite Mebeverine acid	Drug Metabolite	Neurological Disease
Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine. Mebeverine is an antispasmodic agent. Mebeverine acid is a valuable marker of oral exposure to Mebeverine .

HY-122520

Fentonium bromide	Others	Neurological Disease
Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions .

HY-100562

Flopropione	5-HT Receptor COMT	Neurological Disease
Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor . Flopropione also as an antispasmodic agent .

HY-107349S

Fenoverine-d8 Spasmopriv-d₈	Calcium Channel	Neurological Disease
Fenoverine-d₈ is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].

HY-B1806A

Tridihexethyl chloride Pathilon chloride	mAChR	Neurological Disease Inflammation/Immunology
Tridihexethyl (Pathilon) chloride is an orally active anticholinergic agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus .

HY-16489

Terodiline	Potassium Channel mAChR Calcium Channel	Metabolic Disease
Terodiline, an antispasmodic agent, blocks hERG current with the IC₅₀ of 375 nM. Terodiline has both anticholinergic and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability. Terodiline can be used for the research of urinary incontinence .

HY-B0549A

Flavoxate hydrochloride Rec-7-0040; DW61	Phosphodiesterase (PDE) Calcium Channel mAChR	Neurological Disease
Flavoxate hydrochloride is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate hydrochloride is an *antispasmodic* agent and muscarinic mAChR antagonist. Flavoxate hydrochloride shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate hydrochloride can be used for the research of overactive bladder (OAB) and lower urinary tract infections .

HY-B0549

Flavoxate Rec-7-0040 free base; DW61 free base	Phosphodiesterase (PDE) Calcium Channel mAChR	Neurological Disease
Flavoxate is a potent and competitive phosphodiesterase (PDE) inhibitor. Flavoxate is an *antispasmodic* agent and muscarinic mAChR antagonist. Flavoxate shows moderate calcium antagonistic activity and local anesthetic effect. Flavoxate can be used for the research of overactive bladder (OAB) and lower urinary tract infections .

HY-12752

Alimemazine Trimeprazine	Histamine Receptor	Neurological Disease Inflammation/Immunology
Alimemazine is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist.Alimemazine (Trimeprazine) is also acts as a partial agonist against the histamine H1 receptor (H1R) and other GPCRs. Alimemazine displays antiserotonin, antispasmodic, and antiemetic properties .

HY-14621

Zingerone 2 Publications Verification Vanillylacetone; Gingerone	NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-B1339

Dicyclomine hydrochloride Dicycloverine hydrochloride	mAChR	Neurological Disease
Dicyclomine hydrochloride is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine hydrochloride shows high affinity for muscarinic M1 receptor subtype (K_i=5.1 nM) and M2 receptor subtype (K_i=54.6 nM) in brush-border membrane and basal plasma membranes, respectively . Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo .

HY-B1339A

Dicyclomine Dicycloverine	mAChR
Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (K_i=5.1 nM) and M2 receptor subtype (K_i=54.6 nM) in brush-border membrane and basal plasma membranes, respectively . Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo .

HY-B1339AS

Dicyclomine-d4 Dicycloverine-d₄	mAChR
Dicyclomine-d₄ is the deuterium labeled Dicyclomine[1]. Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively[2]. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo[3].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N4113

Glycycoumarin	Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer	Keap1-Nrf2 AMPK
Glycycoumarin is a potent *antispasmodic* agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits antispasmodic activity. Glycycoumarin also has hepatoprotective effect. Glycycoumarin can be used for the research of abdominal pain and liver diseases .

HY-100562

Flopropione	Neurological Disease Classification of Application Fields Labiatae Source classification Phenols Polyphenols Plants Picris hieracioides L. Disease Research Fields	5-HT Receptor COMT
Flopropione is a 5-HT receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor . Flopropione also as an antispasmodic agent .

HY-14621

Zingerone 2 Publications Verification Vanillylacetone; Gingerone	Zingiber officinale Roscoe Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Plants Disease Research Fields Inflammation/Immunology Zingiberaceae	NF-κB
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

Cat. No.	Product Name	Chemical Structure

HY-107349S

Fenoverine-d8
Fenoverine-d₈ is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].

HY-B1339AS

Dicyclomine-d4
Dicyclomine-d₄ is the deuterium labeled Dicyclomine[1]. Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively[2]. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo[3].

Dicyclomine-d4

Dicyclomine-d₄ is the deuterium labeled Dicyclomine[1]. Dicyclomine (Dicycloverine) is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine (Dicycloverine) shows high affinity for muscarinic M1 receptor subtype (Ki=5.1 nM) and M2 receptor subtype (Ki=54.6 nM) in brush-border membrane and basal plasma membranes, respectively[2]. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo[3].

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